Corneal Diseases
Conditions
Keywords
Intensive care, corneal damage, prevention, nursing protocol
Brief summary
60% of the patients hospitalized in intensive care and sedated suffer from insufficient inferior eyelid occlusion. Thus, they are at risk for corneal damage (estimated risk 20% to 57%). The prevention of such corneal damage can be done using several techniques (artificial tears, eyelid occlusion dressing, aqueous gel). The efficacy of these techniques has never been compared in a rigorous study. Therefore it is not yet possible to determine an evidence-based strategy to prevent corneal damage in intensive care patients. This study aims at assessing the efficacy of primary prevention of corneal lesions in intensive care patients, in order to elaborate an evidence-based nursing protocol.
Interventions
DEVICEAqueous Gel
1 drop of Dexpanthenol® 0.2% aqueous gel in the eye every 6 hours
DEVICEEyelid Occlusion Dressing
Eyelid occlusion using pro-ophta® eyelid occlusion dressing, dressing to be verified every 6 hours and replaced daily
DEVICEArtificial Tears
1 drop of Phylarm® artificial tears in the eye every 6 hours
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* adult patient * hospitalized in an intensive care unit * tracheal intubation and mechanical ventilation since less than 24 hours, with an expected duration of artificial ventilation superior to 72h
Exclusion criteria
* Patient currently treated by eyedrops for glaucoma * antecedent of corneal transplant * ocular prosthesis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of corneal lesions (grade > 0 in the Mercieca classification) | participants will be followed for the duration of stay in intensive care unit, an expected average of 1 week |
Countries
France
Outcome results
None listed