Hypertension, Prostatic Hyperplasia
Conditions
Keywords
Transurethral Resection of Prostate
Brief summary
The known correlation between benign prostatic hypertrophy (BPH) and hypertension could be explained by 3 theoretical pathway models. Whether hypertension causes BPH, BPH causes hypertension or the two are caused by a common factor is currently unknown. In this study it will be investigated whether hypertension is due to the direct effects of infravesical obstruction to urinary outflow in patients with benign prostatic hyperplasia. The approach will be blood pressure measurement in patients who will have a resection of the prostate.
Interventions
PROCEDURE24-hr ambulatory blood pressure measurement
Sponsors
Norwegian University of Science and Technology
St. Olavs Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
No minimum to 65 Years
Healthy volunteers
No
Inclusion criteria
* Listed for inguinal hernia repair or hydrocele repair or transurethral resection of the prostate * signed informed consent
Exclusion criteria
* Treatment with antihypertensive medication that has been started within 3 months of inclusion. * Treatment with antihypertensive medication that has been started after inclusion and before final blood pressure measurements have been obtained 6 months after operation. * Any reason that the investigator deems that the participant will not comply with follow-up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in blood pressure | 7,5 months | one measurement 6 weeks pre-surgery, and ambulatory measurement during 6 months post-surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| prostate symptom severity assessed by 'International prostate severity score' (questionnaire) | 7,5 months | assessed by 'International prostate severity score' (questionnaire) |
Countries
Norway
Outcome results
None listed