Clinical and Radiological Results of Osteochondral Repair Using MaioRegen in Knee and Ankle Surgery

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02345564

Enrollment

Registered

2015-01-26

Start date

2012-03-31

Completion date

2015-12-31

Last updated

2015-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Degenerative Lesion of Articular Cartilage of Knee, Osteochondral Lesion of Talus

Brief summary

Osteochondral lesions in knee and ankle are injuries commonly seen in young patients. MaioRegen fleece is a cartilage substitute which can be used in circumscribed defects. This prospective study follows patients treated with MaioRegen implants from pre-surgery until 24 months post-surgery.

Interventions

DEVICEimplantation of MaioRegen fleece into osteochondral lesion

arthroscopic localization of lesion, arthroscopic guided mini-arthrotomy and implantation of defect sized MaioRegen fleece

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

16 Years to 65 Years

Healthy volunteers

Inclusion criteria

* single osteochondral lesion in knee/ankle (2-4 sq cm)

Exclusion criteria

* multiple osteochondral lesions * pre-existing injuries/arthropathies

Design outcomes

Primary

Measure	Time frame	Description
MRI imaging - gap between cartilage-implant surface in mm	18 months post surgery	ingrowth of fleece into the cartilage

Secondary

Measure	Time frame	Description
clinical outcome measurement	pre-surgery	Lysholm Knee Score Cincinatti Knee Scale IKDC Knee Score AOFAS Hindfoot Score Foot&Ankle Disability Index

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026