Cancer
Conditions
Brief summary
Analysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.
Detailed description
The accurate and detailed knowledge of the changes (e.g., anatomically/biologically intra- and inter-fraction changes) to be obtained from this study would allow the research team to determine how Adaptive Radiation Therapy (ART) should be performed for a given tumor site/type. Radiation oncologists then can choose a proper ART strategy for a given tumor type to account for the anatomic/biological intra- and inter-fraction changes, improving accuracy of radiation therapy delivery, and in turn reducing treatment related toxicities and/or improving tumor local control.
Interventions
RADIATIONRadiation Therapy
Radiation therapy plans for cancer patients who have completed treatment.
Sponsors
Medical College of Wisconsin
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
°Completed radiation therapy
Exclusion criteria
°Subjects who refuse voluntary participation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes of volumes from baseline of organs at risk during and after radiation therapy. | 2 years | Changes of organs at risk volumes (cm\^3) during and after radiation therapy. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes of volumes from baseline or tumors during and after radiation therapy. | 2 years | Changes of tumor volumes (cm\^3) during and after radiation therapy. |
Countries
United States
Contacts
CONTACTMedical College of Wisconsin Cancer Center Clinical Trials Office
CONTACTEric Paulson, PhD
PRINCIPAL_INVESTIGATOREric Paulson, PhD
Medical College of Wisconsin
Outcome results
None listed