Malignant Neoplasm of Fallopian Tube
Conditions
Keywords
Fallopian tubal cancer, high grade serous , ovarian cancer
Brief summary
PCR for chlamydia DNA is done in paraffin blocks of cases of primary tubal cancer and is compared to cases of high grade serous ovarian cancer and normal tubes .
Detailed description
The investigators shall review the early cancer detection unite pathology records for the past 10 years , for cases diagnosed with primary Fallopian tube cancers , cases of high and low grade serous ovarian cancer and cases underwent hysterectomy and salpingectomy for non oncological reasons. Paraffin blocks for suitable selected patients will be examined histologically to confirm the primary diagnosis . Chlamydia DNA in these paraffin blocks of the Fallopian tubes and ovarian tissues will be examined using PCR techniques . The possible correlation between the presence of Chlamydia DNA and the ovarian serous tumours and primary tubal cancer will be analyzed statistically .
Interventions
OTHERPCR for chlamydia DNA in primary tubal cancer
PCR for presence of chlamydia DNA in paraffin blocks retrieved for tubal and ovarian tissues in all groups
Sponsors
Ain Shams University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* any patient with primary tubal cancer and high grade serous cancer and normal tubes.
Exclusion criteria
* clinical pelvic inflammatory disease * salpingectomy for ectopic
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of chlamydia DNA in tubal and ovarian tissues | Up to 24 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Presence of concomitant tubal cancer with high grade serous ovarian cancer | Up to 8 weeks |
Countries
Egypt
Outcome results
None listed