Stillbirth
Conditions
Keywords
Group B Streptococcus, stillborn
Brief summary
This is a descriptive study to determine the role of fetal GBS disease as a cause for stillbirths
Detailed description
A prospective, descriptive study will be undertaken involving mothers who have a stillbirth at Chris Hani Baragwanath Academic Hospital (CHBAH), a secondary-tertiary care hospital, from 2014 up until 2016.
Interventions
None listed
Sponsors
University of Witwatersrand, South Africa
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 1 Days
Healthy volunteers
No
Inclusion criteria
* Pregnant women delivering a stillbirth at CHBAH * Participants aged ≥18 years * Able to understand and comply with planned study procedures * Provides written informed consent (either generic ICF or V98\_28OBTP)
Exclusion criteria
* Refuses to consent to study participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determine the number of stillbirths who have GBS isolated from cord blood, gastric aspirates, placenta and/ or skin swabs | Birth |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of stillbirths occurring at CHBAH, and identify potential causes of the stillbirths (maternal and obstetric risk factors) | Birth | To determine the epidemiology of stillbirths, including identification of maternal risk-factors |
| Number of stillbirths related to a probable Infectious cause | Birth | To determine the proportion of stillbirths that are associated with common fetal in-utero infections including; Syphilis (Treponema pallidum), Klebsiella sp, E. Coli |
Countries
South Africa
Outcome results
None listed