Long Protocol and Growth Hormone in Poor Responders

Growth Hormone Adjuvant Therapy With Long Down Regulation Protocol in Poor Responders Undergoing In Vitro Fertilization Cycles: a Randomized Control Trial

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02338206

Enrollment

240

Registered

2015-01-14

Start date

2015-03-31

Completion date

2017-11-15

Last updated

2017-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

infertility

Brief summary

The long down regulation protocol is widely used in the in vitro fertilization cycles, now it will be assessed regarding its efficacy, in poor responder females undergoing in vitro fertilization cycles, alone and after the addition of growth hormone.

Interventions

DRUGGrowth hormone

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 44 Years

Healthy volunteers

Yes

Inclusion criteria

* Poor responder females are those who posses two out of these three criteria: * Female age ≥40 years * Females who have at least one previous cancelled IVF cycle * POR according to AFC ≤ 5 or low AMH value.

Exclusion criteria

* Females over 45 years * Females with FSH more than 20 IU/l * Females with previous ovarian surgery * Females suffering from causes of infertility other than poor ovarian response * Females refusing to be enrolled in the study

Design outcomes

Primary

Measure	Time frame	Description
Live birth rate	12 months	Fresh, Frozen, Cumulative

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 6, 2026