Epistaxis, Nasal Obstruction, Rhinitis, Vasomotor
Conditions
Brief summary
The purpose of this study is to learn whether nasal saline irrigation is beneficial to patients undergoing radiation therapy for oropharyngeal cancer.
Detailed description
In this study, subjects are randomized to one of two study arms. They are either randomized to receive nasal saline irrigation treatment (treatment group) or not to receive any nasal irrigation treatment (control group). Subjects randomized to the treatment group will be provided with saline packets to mix with water. All study subjects will be asked to complete questionnaires during the study. If a subject completes all study related activities, their total length of participation in the study will last about 2 months.
Interventions
OTHERSaline mixture
premeasured salt packets mixed with distilled water
Sponsors
Lisa Shnayder
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients seen in the KUMC Ear, Nose and Throat clinic with oropharyngeal cancer that have undergone radiation therapy as the primary treatment
Exclusion criteria
* Patients that are at high risk for infection secondary to nasal irrigation * Patients with autoimmune disease or immune deficiency
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in quality of life, measured using Sino-Nasal Outcome Test (SNOT-20) summary scores | Change from Baseline to Month 2 | Outcome measured using Sino-Nasal Outcome Test (SNOT-20) summary scores. Scores will be collected at the baseline visit and again on the Month 2 visit. Outcome represented as a change in mean summary scores between the two visits. Scores can range from 0-5 with 0 being the best and 5 being the worst. |
Countries
United States
Outcome results
None listed