HIV
Conditions
Keywords
Enrollment in HIV care, Recently detected HIV-positive, specialized health care clinics, Ukraine
Brief summary
This study proposes to assess whether a modified Antiretroviral Treatment Access Study intervention, proved to be effective in the U.S. and based on the nurse case management approach, can impact the enrollment in HIV care of recently detected HIV-positive patients in specialized health care clinics in three regions in Ukraine, using the existing local infrastructure. The proposed study addresses a significant public health issue of non-/late enrollment of HIV-positive persons in HIV care and treatment.
Detailed description
Individual, parallel, two-arm, 1:1 RCT. The study participants were recruited between October 2015 and December 2016 at 9 clinics located in Dnipropetrovsk region (Dnipropetrovsk Regional Narcological Dispensary; Dnipropetrovsk Regional Dermatovenereologic Dispensary; Kryvyi Rih Infectious Disease Clinic No. 1), Mykolaiv region (Mykolaiv Regional Narcological Dispensary; Mykolaiv Regional Dermatovenereologic Dispensary; Mykolaiv Regional Infectious Disease Clinic), and Odesa region (Odesa Regional Dermatovenereologic Dispensary; Odesa Infectious Disease Clinic; Odesa Regional Center of Mental Health). These three types of clinical sites (treating addiction, sexually transmitted infections \[STIs\], and infectious diseases \[IDs\]) were located in the regions with the highest HIV prevalence in Ukraine, but were not co-located with HIV care facilities. Participants assigned to the standard of care (SOC) arm and the MARTAS arm received referrals to the local AIDS Centers (Dnipropetrovsk Regional AIDS Center, Kryvyi Rih AIDS Center, Mykolaiv Regional Center for Palliative Care and Integrated Services (former Mykolaiv AIDS Center), and Odesa Regional AIDS Center) or their departments (Trust offices) located in each study region. Investigators affiliated with The Ukrainian Institute on Public Health Policy (UIPHP) were responsible for all aspects of study design, management, and analysis.
Interventions
BEHAVIORALModified Antiretroviral Treatment Access Study intervention
Sponsors
Ukrainian Institute on Public Health Policy
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 18+ years; * Tested HIV-positive * Fluent in Russian or Ukrainian; * Able to read/understand and sign an informed consent
Exclusion criteria
* Enrolled in HIV care; * Plan to move out of the study region before the end of their follow-up period * Cognitive impairment * Have pending legal issues, independent of their lifetime history of incarceration * Subject is a part of another intervention or/and research study with similar linkage-to-care objectives
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The proportion of referred intervention patients who enroll in HIV care | 3 months | Linkage (registration) to HIV care within the 3-month period after study enrollment-both self-reported and confirmed by the medical record. |
Countries
Ukraine
Outcome results
None listed