The Influence Factors of Ovarian Response in PCOS Patients With IVF-ET Treatment

The Influence Factors of Ovarian Response in Polycystic Ovary Syndrome Patients(PCOS) With In Vitro Fertilization and Embryo Transfer (IVF-ET) Treatment

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02331758

Enrollment

1000

Registered

2015-01-06

Start date

2015-01-31

Completion date

2015-09-30

Last updated

2015-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Syndrome

Brief summary

The purpose of this study is to explore the factors which affect ovarian response of PCOS patients with IVF-ET treatment, in order to provide predictive clinical index for the outcome of IVF-ET treatment in PCOS patients. After figuring out the controllable factors, researchers would be able to educate PCOS patients and improve the success rate while reducing the incidence of complications during the treatment at the same time.

Detailed description

Statistics of PCOS patients like age, BMI index and others would be collected. Through distributing questionnaires and query of past cases and collecting data recorded during the ovulation process like monitoring fluctuations in blood and ultrasonic monitoring results, researchers obtain the risk factors of the occurence of Ovarian Hyperstimulation Syndrome(OHSS) in IVF-ET treatment in PCOS patients and set up an OHSS prediction model, choose controllable factors in order to make up guidance and have intervention on patients with PCOS accordingly. The investigators expect this could improve the success rate of IVF-ET treatment in patients with PCOS, provide clues and assist to reduce the risk of the therapy.

Interventions

BEHAVIORALLifestyle Counseling

The investigators do lifestyle counseling for PCOS patients and monitor the factors to normal level, like BMI, serum index etc.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* Clinical diagnosis of PCOS * Long schedule time of Luteal phase * Available to trace * Normal Prolactin level with contraceptive treatment in recent 3 months

Exclusion criteria

* Unwilling to participate

Design outcomes

Primary

Measure	Time frame	Description
oocyte number	3 Month	Affect the outcome of IVF-ET treatment

Secondary

Measure	Time frame	Description
Success Rate	3 Month	The success rate of IVF-ET treatment elevated
OHSS complication	3 Month	The number of OHSS patients reduced

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026