Timing of HCG Administration in IUI Cycles

Timing of Human Chorionic Gonadotropin Administration in Intrauterine Insemination Cycles

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02330705

Enrollment

225

Registered

2015-01-05

Start date

2015-01-31

Completion date

2019-08-31

Last updated

2019-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

Intrauterine insemination, IUI, HCG

Brief summary

Evaluation of the effect of altering the timing of human chorionic gonadotropin (HCG) administration on the clinical pregnancy rate in intrauterine insemination (IUI) cycles.

Detailed description

Women will be randomly divided into 3 groups; the first group will undergo IUI at the time HCG administration, the second group will undergo IUI 12 hours after HCG administration and the third group will undergo IUI 34-36 hours after HCG administration.

Interventions

DRUGHCG

Women will be given HCG before IUI

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 35 Years

Healthy volunteers

Inclusion criteria

* Mild male factor infertility or unexplained infertility.

Exclusion criteria

* Advanced male factor infertility. * Polycystic ovary syndrome (PCOS) as defined by the Rotterdam criteria. * Endometriosis. * Tubal disease. * Uterine abnormalities or myoma. * Previous uterine surgery. * Metabolic or hormonal abnormalities.

Design outcomes

Primary

Measure	Time frame	Description
Clinical pregnancy rate	4-6 weeks after IUI	Number of clinical pregnancies (defined as presence of at least one intrauterine gestational sac with fetal pole and cardiac activity on TVS scan at 4-6 weeks after IUI) divided by the number of IUI cycles

Countries

Egypt

Contacts

Primary ContactMohamed I Eid, Dr

dr_moh_eid@yahoo.com+201225401274

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026