Common Bile Duct GallStones, Common Bile Duct Gall Stones
Conditions
Keywords
duodenal-biliary reflux
Brief summary
ERCP is the primary choice for removal of common bile duct stone (CBDS) currently. However, 4-24% patients underwent recurrence after successful clearance of CBDS. Stone re-formation due to chronic inflammation of biliary duct is generally considered an important cause of CBDS recurrence, which is associated with duodenal-biliary reflux (DBR) after sphincterotomy. Although it was believed that DBR was the important cause of CBDS recurrence, the direct evidence was still lacking. Here we conducted a case control study to investigate the DBR rate in patients with recurrent CBDS after ERCP.
Interventions
OTHERstandard barium meal examination
All eligible patients received standard barium meal examination, MRCP and enhanced abdominal CT.
Sponsors
Air Force Military Medical University, China
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients with common bile duct stone underwent successful stone removal by ERCP in Xijing Hospital of Digestive Diseases.
Exclusion criteria
* Gallbladder stones or hepatolithiasis; * Stenosis of biliary duct; * Incomplete common bile duct stone removal by ERCP; * Common bile duct stent; * Unable to provide informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duodenal-biliary reflux rate | up to 6 months | The proportion of patients with barium reflux into bile duct during the standard barium meal examination. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Distal common bile duct angle | up to 6 months | MRCP revealed the first angulation from the ampullary orifice along the course of the common bile duct stone. |
| Maximal CBD diameter | up to 6 months | Maximal CBD diameter was determined by MRCP. |
| Peripapillary diverticulum | up to 6 months | Peripapillary diverticulum was defined endoscopically as the presence of a diverticulum within a 2-cm radius from the papilla and was divided into 2 types in terms of the relation between the papilla and diverticulum: type A, papilla located on the inner rim of the diverticulum or papilla located deep within the diverticulum; and type B, papilla located outside the diverticulum. |
| Pneumobilia | up to 6 months | Pneumobilia were determined by CT |
Countries
China
Outcome results
None listed