Alcohol Consumption and Gallbladder Cancer

Alcohol Consumption and Gallbladder Cancer: Case-control Study in Jeju Island, Korea.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02326948

Enrollment

156

Registered

2014-12-30

Start date

2014-08-31

Completion date

2014-11-30

Last updated

2014-12-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gallbladder Cancer

Keywords

Gallbladder cancer, Case-control study, Risk factor, Alcohol consumption, Polypoid lesions of gallbladder, Biliary stone

Brief summary

This case-control study matched by age and sex was performed to evaluate the region specific risk factors for gallbladder cancer in Jeju island, Korea.

Detailed description

In order to estimate region-specific risk factors for gallbladder cancer (GBC) in Jeju island, Korea the investigators performed a case-control study. Among 124 GBC patients and 7088 health controls, the investigators randomly selected 78 cases and 78 age-sex matched controls (1:1 matching) and compared their demographic features, combined diseases, and personal histories about known risk factors until now.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Case group : newly diagnosed gallbladder cancer patients in Digestive Disease Center, Department of Internal Medicine in Cheju Halla General Hospitalduring 2008-2013 * Control group : 1:1 age-sex matched controls underwent health care screening program in Department of Health Promotion Center in Cheju Halla General Hospital for 2008-2012.

Exclusion criteria

* Case group Ambiguous diagnosis primary tumor involving common bile duct follow up loss without pathologic confirmation Incomplete clinical records Couldn't be assessed the results of operation or radiologic imaging. * Control group Cases unavailable for gallbladder imaging (abdominal ultrasonography ,computed tomography, or magnetic resonance imaging) Cases underwent previous cholecystectomy before enrollment.

Design outcomes

Primary

Measure	Time frame
Number of participants with alcohol consumption	Up to 3 years

Other

Measure	Time frame
Number of participants with biliary stone diseases	Up to 3 year
Number of participants with polypoid lesions of gallbladder	Up to 3 years

Countries

South Korea

Outcome results