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RV Function Evaluation Assessed by Strain and Validated by MRI

RV Function by Strain and MRI

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02326701
Enrollment
200
Registered
2014-12-29
Start date
2014-12-31
Completion date
Unknown
Last updated
2014-12-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Right Ventricular Function

Brief summary

Echocardiographic assessment of right ventricular function is an important diagnostic tool, and is a challenge due to the unique structure and anatomy of the right ventricle. Lately a new technique has been developed and used for evaluating both the left and the right ventricle function. This technique, called two dimensional (2D) speckle tracking, is based on detecting speckles in the myocardial tissue and using them as acoustic markers. The movement of these speckles represents the movement of the tissue, and allows us to evaluate its function, contraction and relaxation, this by calculating the strain rate, which is the speed of the speckles, and the strain, which is the distance between them. In the last few years this technique has been used to evaluate the systolic function of the right ventricle in several pathological conditions, such as pulmonary hypertension, pulmonary embolism and amyloidosis. Nonetheless, so far there has been little data on the normal RV strain and strain rate values. In this study the investigators aim to validate two dimensional (2D) speckle tracking measurements of the RV function by comparing them to strain measurements by cardiac MRI. Each patient performing cardiac MRI for any indication will perform an echocardiography examination in addition, and strain analysis performed on the cardiac MRI will be compared with two dimensional speckle tracking analysis performed on the echocardiography.

Interventions

None listed

Sponsors

Hadassah Medical Organization
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age: More than 18

Exclusion criteria

* Age: Children * Unconcious patients.

Design outcomes

Primary

MeasureTime frameDescription
Correlation of 2D Echo and Echo strain measurements versus MRI measurements1 yearRV dimensions, RV function, RV strain measurements compared to MRI measurements

Secondary

MeasureTime frameDescription
Rehospitalization2 yearsTime from index event to timing and length of rehospitalization (based on hospital data and completed with phone interview when necessary)

Countries

Israel

Contacts

Primary ContactRonen Beeri, MD
rbeeri@hadassah.org.il00972508573400
Backup ContactDan Gilon, MD
dangi@ekmd.huji.ac.il00972507874011

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026