Multimodal Monitoring in Patients With Spontaneous Intracerebral Hemorrhage

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02326571

Enrollment

Registered

2014-12-29

Start date

2014-12-31

Completion date

2016-06-20

Last updated

2017-04-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Hemorrhage

Keywords

EEG, Cortical Spreading Depression, Cerebral Hemorrhage, miRNA, Reactivity in EEG, Multimodal monitoring

Brief summary

Spontaneous intracerebral bleeding also known as spontaneous intracerebral hemorrhage (sICH) constitute 10-15 % of all apoplexies. The Prognosis is considerably worse than it is for the larger population of patients suffering from cerebral thrombosis. Development of brain edema seemingly contributes to the disadvantageous prognosis. However, the mechanisms behind is only understood fragmentarily. By using multimodal neuro monitoring, the investigators seek to investigate electrophysiological and metabolic processes, which seem to accompany the formation of edema and clinical deterioration in patients suffering from sICH.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Diagnosis: spontaneous intracerebral hemorrhage verified by CT * Clinical indication for craniotomy or craniectomy * Admitted to the hospital within 24 hours from assumed ictus * Age over 18 years

Exclusion criteria

* Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Secondary brain injury	10 days	Assessed by GCS, CAM-ICU, mRS, Imaging, EEG background activity.

Countries

Denmark

Outcome results