Chronic Obstructive Pulmonary Disease(COPD)
Conditions
Keywords
respiratory muscle training, respiratory muscle strength, respiratory endurance test, 6-minute walking test
Brief summary
The study will investigate the effects of different training types ,including combined inspiratory with expiratory pressure threshold training,inspiratory pressure threshold training on patients with chronic obstructive airway disease and investigate whether expiratory pressure threshold training associated with inspiratory pressure threshold training would be better than inspiratory pressure threshold training alone, with regard to exercise capacity, respiratory muscle strength and endurance.
Detailed description
We will study 60 patients diagnosed of chronic obstructive pulmonary disease.The monitoring will be done for 8 weeks. Pressure-threshold respiratory trainers were calibrated to provide different loads according to the patients against inspiration (IMST) or expiration (EMST). Those chronic obstructive pulmonary disease clinically stable patients stratified from mild to very severe GOLD stages, were blinded to randomly divided into 3 different groups: a)control group:without any training;b) inspiratory and expiratory pressure threshold training group: trained with the pressure threshold trainer twice time daily with 15minutes' duration;c)inspiratory pressure threshold training group:trained with the pressure threshold trainer twice time daily with 15 minutes' duration,different from the b group,the expiratory pressure threshold is calibrated at 0.
Interventions
DEVICEinspiratory pressure training group
The respiratory pressure load device can be provided different loads to perform inspiratory and expiratory pressure training.In the study,pressure-threshold respiratory trainers were calibrated to provide different loads against inspiration (IMST) .
DEVICEmixed training group
The respiratory pressure load device can be provided different loads to perform inspiratory and expiratory pressure training.In the study,pressure-threshold respiratory trainers were calibrated to provide different loads against inspiration (IMST) and expiration(EMST).
Sponsors
Zhujiang Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Clinically stable COPD with diagnosis of forced expiratory volume at one second(FEV1)/forced vital capacity(FVC) \< 70%
Exclusion criteria
Cancer Unstable heart disease Neuromusculoskeletal disorder mental disorder Active smokers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| respiratory muscle strength measurements | baseline and 8 weeks |
Secondary
| Measure | Time frame |
|---|---|
| respiratory muscle endurance text | baseline and 8 weeks |
| 6-minute walking test | baseline and 12 weeks |
| perceived exertion for leg fatigue (Borg-scale) | baseline and 8 weeks |
| modified british medical research council(mMRC) questionnaire | baseline and 8 weeks |
Countries
China
Contacts
Primary ContactLiqing Wang, Doctor
Outcome results
None listed