CMV Intensive Care Units

A Prospective Monitoring Study of Cytomegalovirus Infection in Immunocompetent Critical Heart Surgery Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02324244

Enrollment

150

Registered

2014-12-24

Start date

2012-10-31

Completion date

2013-05-31

Last updated

2014-12-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CMV Infection

Keywords

Cytomegalovirus, critical patient, ICU, immunocompetent, clinical suspicion, risk factors

Brief summary

Prospectively assessment of CMV viremia by real-time polymerase chain reaction (PCR) in a broad cohort of consecutive immunocompetent adults admitted to a major heart surgery intensive care unit (MHS-ICU) with the goal of determining the epidemiology, risk factors, and clinical significance of CMV infection.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Agreeing to participate in the study * Age of at least 18 years * Admission to the MHS-ICU for at least 72 hours

Exclusion criteria

* Inability to give informed consent * Age younger than 18 years * AIDS * Pregnancy * Organ or bone marrow transplant, receipt of immunosuppressive therapy including corticosteroids within 30 days, and cancer or hematologic malignancy treated with radiotherapy or chemotherapy

Design outcomes

Primary

Measure	Time frame
incidence number of participants with a positive CMV positive result	month 8

Secondary

Measure	Time frame	Description
risk factors for CMV reactivation	month 8	—
mortality by day 30	month 8	composite endpoint. hospitalization or death by day 30
prolonged hospitalization . More than 30 days	month 8	—

Countries

Spain

Outcome results