Anesthesia
Conditions
Brief summary
This study is to observe whether transcutaneous electrical stimulation at specific acupoints could improve the quality of emergence in patients undergoing robotic laparoscopic gynecologic surgery.
Detailed description
During robotic laparoscopic gynecologic surgery, the patients are put in an extremely trendelenburg positon. And a long duration of this position could lead to delayed emergence or agitation. Stimulation at some acupoints were reported to improve homeostasis. In this study we tend to observe whether transcutaneous electrical stimulation at specific acupoints could improve the quality of emergence in patients undergoing robotic laparoscopic gynecologic surgery.
Interventions
OTHERacupoint stimulation
stimulation is given at acupoints
stimulation is given at acupoints
OTHERelectrode attached
electrodes are attached to skin
DEVICEelectrical stimulation
electrical stimulation is given through electrodes attached to th skin
Sponsors
Air Force Military Medical University, China
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients scheduled for robotic laparoscopic gynecologic surgery under general anesthesia * Patients with written informed consent
Exclusion criteria
* Patients with difficulty in communication * Patients with disease of central nervous system
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time to awake | from end of inhaling sevoflurane to departing from postanesthesia care unit(PACU),an anticipated average of 1 hour | time to open eyes to verbal command |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time to extubation | from end of inhaling sevoflurane to departing from PACU,an anticipated average of 1 hour | — |
| QoR-15 | from end of inhaling sevoflurane to 24h after surgery,an anticipated average of 24 hour | Score of quality of recovery using a 15 items questionaire |
| residual sedation | from arriving at PACU to departing from PACU,an anticipated average of 30min | — |
| PONV | from arriving at PACU to departing from PACU,an anticipated average of 30min | postoperative nausea and vomiting in the PACU |
| Richmond Score | from end of inhaling sevoflurane to departing from PACU,an anticipated average of 1 hour | status of the patients during emergence |
| serum Aquaporin 4 | from before anesthesia to after surgery, an anticipated average of 4 hours | level of serum Aquaporin 4 before anesthesia and at the end of the surgery |
| serum MMP9 | from before anesthesia to after surgery, an anticipated average of 4 hours | level of serum Matrix metallop roteinase before anesthesia and at the end of the surgery |
| serum S100β | from before anesthesia to after surgery, an anticipated average of 4 hours | level of serum S100β before anesthesia and at the end of the surgery |
| VAS score | from arriving at PACU to departing from PACU,an anticipated average of 30min | visual analogue score of pain in the PACU, scored 0-10 |
Countries
China
Outcome results
None listed