Anesthesia
Conditions
Keywords
Dose-response relationship, Drug
Brief summary
To determine the median effective concentration of ropivacaine hydrochloride for ultrasound-guided supraclavicular brachial plexus block. The result can provide reference for choosing appropriate drug concentration in clinical anesthesia.
Interventions
DRUGropivacaine
Sponsors
Yu Shan
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 64 Years
Healthy volunteers
Yes
Inclusion criteria
* ASA I or II
Exclusion criteria
* upper limb paresthesia * allergic to local anesthetics * surgery history of clavicle * BMI\>30kg/m\^2
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the affection of nerve block | 30 minutes | The anesthetic efficacy of five nerves, respectively named lateral antebrachial cutaneous nerve, medial cutaneous nerve of the forearm, radial nerve, median nerve, and ulnar nerve was assessed within 30 min after anesthesia. The next concentration of ropivacaine was adjusted according to the response of the previous patient using up-down sequential allocation. |
Countries
China
Contacts
Primary ContactShan Yu
Outcome results
None listed