Epilepsy, Tumor
Conditions
Brief summary
The investigators want to characterize high-frequency oscillations (HFOs) in intracranial recordings, which may occur as markers of epileptogenic tissue and also under physiological stimulation. The investigators want to show that recording of high-frequency oscillations (HFOs) is feasible in our project population both intraoperatively and during presurgical physiological conditions.
Interventions
BEHAVIORALcognitive testing
patients perform simple tasks like watching a video or memorizing items
Sponsors
University of Zurich
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* Patients intend to be treated at the Klinik für Neurochirurgie * Patients fall into one of the patient groups: (1) Patients with symptomatic epilepsy with focal and/or secondary generalized seizures resistant to medication where a neurosurgical resection is considered as an intervention of epilepsy surgery. (2)Patients where a tumor is planned to be resected that has caused preoperative seizures. (3) Patients where a tumor is planned to be resected that has not caused preoperative seizures. * Male and Female subjects 18 years to 99 years of age * Written informed consent after participants' information
Exclusion criteria
* contraindications on ethical grounds * known or suspected non-compliance, drug or alcohol abuse, * enrolment into a clinical trial within last 4 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HFO (high-frequency oscillations) occurrence | 1 week |
Outcome results
None listed