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Measurement of the Oxygen Saturation in the Retinal Vessels With Oxymap

Measurement of the Oxygen Saturation in the Retinal Vessels With Oxymap

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02318641
Enrollment
300
Registered
2014-12-17
Start date
2014-12-31
Completion date
2018-12-31
Last updated
2018-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chorioretinal Disorders in Diseases Classified Elsewhere

Keywords

oxygen consumption, retinal oximetry

Brief summary

Retinal oximetry can be measured with newly developed Oxymap (Oxymap ehf, Reykjavik, Iceland). Briefly, the device simultaneously acquires digital images at two wavelengths and automatically tracks retinal vessels on both images. Retinal vessel oxygen saturation is estimated by spectrophotometric analysis of light reflected from retinal vessels and from the immediately surrounding retina. Oxygen saturation measurements are made on major temporal arteries and veins. Briefly, the first and second degree vessels are used, with the addition of third degree vessels in images where peripapillary haemorrhage prevented analysis close to the optic disc. Vessel segments chosen for analysis are used consistently for consecutive measurements in the same retina.

Detailed description

Retinal oximetry can be measured with newly developed Oxymap (Oxymap ehf, Reykjavik, Iceland). Briefly, the device simultaneously acquires digital images at two wavelengths and automatically tracks retinal vessels on both images. Retinal vessel oxygen saturation is estimated by spectrophotometric analysis of light reflected from retinal vessels and from the immediately surrounding retina. Oxygen saturation measurements are made on major temporal arteries and veins. Briefly, the first and second degree vessels are used, with the addition of third degree vessels in images where peripapillary haemorrhage prevented analysis close to the optic disc. Vessel segments chosen for analysis are used consistently for consecutive measurements in the same retina. Retinal oximetry in various chorioretinal diseases will be measured with Oxymap.

Interventions

DEVICEoximetry

Retinal oximetry will be performed with Oxymap.

Sponsors

Kagawa University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* Healthy eyes and eyes with various chorioretinal diseases, including diabetic retinopathy, retinal vein occlusion, epiretinal membrane, macular hole, inherited chorioretinal diseases, glaucoma, retinal detachment, etc.

Exclusion criteria

* Eye with medial opacity.

Design outcomes

Primary

MeasureTime frame
Change of retinal oxygen saturation from baseline at 6 monthsSix months.

Countries

Japan

Contacts

Primary ContactChika Akuta
kaomie@med.kagawa-u.ac.jp+81878912211

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026