Gait, Unsteady, Muscle Weakness
Conditions
Brief summary
This is a pilot study for evaluating the feasibility of using High Intensity Interval Training in geriatric hospitalized patients compared to the standard current rehabilitation practice.
Detailed description
High Intensity Interval Training (HIIT) has shown a superior effectiveness and efficiency when compared to Moderate Intensity Continuous Training (MICT) in several types of patients and in healthy subjects. There are no data on HIIT in a general geriatric population. This study is a pilot study evaluating the feasibility of using HIIT in geriatric hospitalized patients compared to the standard current rehabilitation practice without HIIT. It is our desire to perform a larger randomized comparative trial between HIIT and MICT if the pilot study proves its feasibility.
Interventions
OTHERhigh intensity interval training-HIIT
HIIT 4 times a week, 30 minutes duration
OTHERTraditionnal group rehabilitation
Traditionnal group rehabilitation, 3 times a week, 1 hour duration
Sponsors
University Hospital, Geneva
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged 65 years and older hospitalized for rehabilitation after an acute medical condition * Expected duration of the rehabilitation ≥ 2 weeks * Ability to follow instructions to perform a Timed up and Go Test * Ability to perform exercises * Willing to participate in 4 sessions of HIIT per week for 2 weeks
Exclusion criteria
* Any acute condition with tachycardia, hypotension or fever. * Abnormal cycle ergometer stress test with * significant ECG modification * decrease of more than 20 mmHg of the blood pressure with exercise * angina * ST depression at a workload \<6 METs * Inability to reach an intensity of 15/20 in the Borg's scale of perceived exertion * Any unresolved acute medical or surgical condition of the following kind: * acute heart failure * acute coronary syndrome \< 1 month * strole \< 1 month * active pericarditis / myocarditis / endocarditis * thromboembolic disease with \< 2 weeks of anticoagulation * acute infection requiring intravenous treatment * ongoing intravenous perfusion * surgery \< 2 months * recent bone fracture * Previous episode of primary cardiac arrest (ie, cardiac arrest that did not occur in the presence of an acute myocardial infarction or during a cardiac procedure). * Severe heart failure (NYHA III and IV) * Severe stenotic or regurgitant valvular disease * Uncontrolled hypertension at rest (SBP≥160mmHg, DBP≥100mmHg) * Uncontrolled dysrhythmia * Non-sustained ventricular tachycardia with exercise * Implanted defibrillator * Obstructive cardiomyopathy * Resting HR \> 100/min * Severe peripheral artery disease * Severe COPD (VEMS \< 50%) * Exercise-induced asthma * Oxygen dependency * Muscular-skeletal anomaly that may limit exercise participation * Delirium * Inability to follow instructions * Inability to consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients who complete the rehabilitation program | 2 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Distance walked in the 6MWT | 2 weeks | — |
| Muscle strength assessed for the upper and lower extremities | 2 weeks | upper extremity : handgrip strength using the Baseline Pneumatic Bulb Hand Dynamometer Pinch Gauge; Lower exremity : knee flexion & extension and ankle flexion & extension using Microfet2™portable Dynamometer. |
| Step variability changes as a measure of quality of ambulation | 2 weeks | Variability measured with GaitRite step analysis system |
Countries
Switzerland
Outcome results
None listed