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Emergence Agitation in Adult Patients After Intracranial Surgery

Emergence Agitation During Recovery From Intracranial Surgery Under General Anesthesia: a Prospective Multicenter Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02318199
Enrollment
400
Registered
2014-12-17
Start date
2015-01-31
Completion date
2015-08-31
Last updated
2015-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intensive Care, Surgical, Neurosurgery, Postoperative Care

Keywords

emergence agitation, intracranial surgery, general anesthesia, incidence, risk factor

Brief summary

Emergence agitation is a frequent complication that can have serious consequences during recovery from general anesthesia. However, agitation has been poorly investigated in patients after craniotomy. In this prospective multicenter cohort study, adult patients will be enrolled after craniotomy and emergence agitation will be evaluated. The incidence, risk factors and outcome will be investigated.

Interventions

PROCEDUREAnesthesia recovery after intracranial surgery

Intracranial surgery for brain tumor, traumatic brain injury, intracranial hemorrhage, subarachnoid hemorrhage and infection.

Sponsors

Beijing Municipal Administration of Hospital, China
CollaboratorUNKNOWN
Capital Medical University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Both supratentorial and infratentorial intradural cranial operations

Exclusion criteria

* Unarousable state (SAS=1) during the first 24 hours after the operation * Interval longer than 24 hours between the end of the surgery and neurosurgical ICU admission

Design outcomes

Primary

MeasureTime frameDescription
Emergence agitation12 hours after operationEmergence agitation is measured by sedation-agitation scale (SAS) and is defined as SAS=5-7.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 5, 2026