Cancer
Conditions
Keywords
elderly cancer patients, chemotherapy toxicity
Brief summary
These days, there is higher proportion of elderly cancer patients. Most of them have comorbidities, borderline performance status and nutritional status. The discontinuation of chemotherapy due to unbearable toxicities was not uncommon. Comprehensive geriatric assessment might be beneficial in selection of suitable elderly patients for chemotherapy administration.
Detailed description
The patients with the age more than 70 years old who scheduled for chemotherapy were enrolled. Geriatric assessment was performed before starting chemotherapy. The toxicity will be recorded prospectively. Predisposing factors of grade 3 and 4 toxicity will be reported.
Interventions
None listed
Sponsors
Mahidol University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
70 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* more than 70 years of age * plan to receive first cycle of chemotherapy * histologically or cytologically proved of cancer
Exclusion criteria
* patients who have concurrent chemoradiotherapy * patients who received local chemotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| predisposing factors of patients developed grade 3 or 4 chemotherapy toxicity | from starting chemotherapy to 1 month after last dose of chemotherapy |
Secondary
| Measure | Time frame |
|---|---|
| incidence of grade 3 or 4 chemotherapy toxicity in elderly | from starting chemotherapy to 1 month after last dose of chemotherapy |
| Factors associated with good quality of life during receiving chemotherapy | from starting chemotherapy to 1 month after last dose of chemotherapy |
Countries
Thailand
Contacts
Primary ContactSuthinee Ithimakin, MD
Outcome results
None listed