Syncope
Conditions
Brief summary
In the present study the investigators evaluate the sensitivity and specificity of passive tilt test in athletes, as well as their haemodynamic responses and autonomic nervous system activity during head-up tilt. Moreover, the investigators try to apply a novel algorithm for the improvement of diagnostic yield of tilt test in athletes.
Detailed description
We examine athletes with a history of reflex syncope and athletes without history of reflex syncope.All subjects undergo a tilt test, for the evaluation of haemodynamics, heart rate variability (HRV) and baroreflex sensitivity.
Interventions
OTHERPassive tilt test
Passive tilt test (without pharmacological provocation). After a horizontal supine rest period of 5 min, the tilt table was inclined at 60° head-up position for 30 min. A positive response was defined according to the European Society of Cardiology guidelines for the diagnosis and management of syncope
Sponsors
Aristotle University Of Thessaloniki
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
14 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* 14-40 years old, * more than 5 years of exercise training experience and competition at a regional level at different sports
Exclusion criteria
* smoking, * recent alcohol consumption, * presence of any chronic disease and use of drugs
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| sensitivity and specificity of tilt test in athletes as measured by the occurence of syncope/presyncope during tilt test | 30 min | sensitivity = number of subjects with syncope/presyncope during tilt test/ number of subjects with a history of reflex syncope, specificity = number of subjects without syncope/presyncope during tilt test/ number of subjects without history of reflex syncope |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Parameters of haemodynamics during tilt test | 30 min | We investigate whether the mean values of parameters of haemodynamics during tilt test can discriminate between athletes with a history of reflex syncope and those without history of syncope |
| Parameters of heart rate variability during tilt test | 30 min | We investigate whether the mean values of parameters of heart rate variability during tilt test can discriminate between athletes with a history of reflex syncope and those without history of syncope |
| Parameters of baroreflex sensitivity during tilt test | 30 min | We investigate whether the mean values of parameters of baroreflex sensitivity during tilt test can discriminate between athletes with a history of reflex syncope and those without history of syncope |
Countries
Greece
Outcome results
None listed