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TEAS to Reduce Propofol Consumption During General Anesthesia

Effect of Transcutaneous Electrical Acupoint Stimulation on Propofol Consumption During General Anesthesia

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02314650
Acronym
TOP
Enrollment
162
Registered
2014-12-11
Start date
2015-08-25
Completion date
2017-12-29
Last updated
2022-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Brief summary

The study is aimed at whether transcutaneous electrical acupoint stimulation (TEAS) during general anesthesia could reduce the need for propofol in patients undergoing minor surgery.

Interventions

stimulation was given at acupoints

stimulation was given at non-acupoints

electrode were attached to skin

Sponsors

Air Force Military Medical University, China
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Patients undergoing minor surgeries including laparoscopic surgery and breast surgery under general anesthesia * Patients with written informed consent

Exclusion criteria

* Patients with difficulty to communicate,including psychiatric disorder and Alzheimer's disease * Patients with drug abuse * Patients with disease of central nervous system * Patients with renal or hepatic dysfunction

Design outcomes

Primary

MeasureTime frame
propofol consumptionfrom induction to the end of surgery,at an average of 1 hour

Secondary

MeasureTime frame
time to awakefrom end of propofol infusion to open eyes to verbal command,at an average of 30 minutes
time to extubationfrom end of propofol infusion to open eyes to verbal command,at an average of 30 minutes
effect site concentration of propofol at awakefrom end of propofol infusion to open eyes to verbal command,at an average of 30 minutes
highest sedation score during stay at postanesthesia care unitfrom end of surgery to discharge from post anesthesia care unit, at an average of 1 hour
nausea and vomiting during stay at postanesthesia care unit30min after surgery

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026