Improvement of Facial Nerve Monitoring in Parotid Surgery by Sugammadex

Influence of Sugammadex on Facial Nerve Monitoring in Parotid Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02314234

Enrollment

Registered

2014-12-11

Start date

2012-01-31

Completion date

2015-12-31

Last updated

2016-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury to Nerve During Surgery

Brief summary

To investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Detailed description

Intraoperative neuromonitoring (IONM) of facial nerve has been applied in identifying and preserving facial nerve during parotid surgery. In this setting, even a single dose of nondepolarizing muscle relaxant may lead to delayed and weakened electromyography (EMG) signal in facial nerve monitoring during parotid surgery. The aim of this study was to investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Interventions

DRUGsugammadex (Bridion)

single dose of sugammadex at skin incision

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* undergoing parotid surgery

Exclusion criteria

* facial nerve injury, renal failure, liver cirrhosis, neuromuscular disease

Design outcomes

Primary

Measure	Time frame
evoked EMG amplitude of facial nerve	up to first post-op day

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026