Lupus Flares and Histological Renal Activity at the End of the Treatment (LuFla)

Lupus Flares and Histological Renal Activity at the End of the Treatment

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02313974

Acronym

LuFla

Enrollment

Registered

2014-12-10

Start date

2014-01-31

Completion date

2018-11-30

Last updated

2016-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lupus Nephritis

Keywords

Lupus Nephritis Treatment, Renal Biopsy in Lupus, Lupus Flare

Brief summary

At this moment, the duration of the treatment in Proliferative Lupus Nephritis has not been determined. Almost 30 percent of patients in total remission during or after a treatment, will relapse in the first 5 years. The factors associated to Renal relapses are not completly known. The investigators think that an histological control study performed to patient with complete remission for a year at the end of a 3 years treatment could help us to know which patients are going to relapse.

Interventions

PROCEDURERenal Biopsy

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

: * Patients between 18 and 70 years old with Proliferative Lupus Nephritis * 3 years treatment with a 6 month induction therapy and 2 years and a half of treatment maintenence

Exclusion criteria

: * Membranous Nephropaty * Mesangial Nephropathy * Less than 3 years treatment * Less than 1 year of complete remission

Design outcomes

Primary

Measure	Time frame	Description
Renal Flares	2 years	Renal relapse after a complete treatment in complete remission patients

Countries

Argentina

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 6, 2026