Prognosis of Inpatients Evaluated for Palliative Radiotherapy

Observational Study of Prognosis of Inpatients Evaluated for Palliative Radiotherapy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02312791

Acronym

PROGRAD

Enrollment

362

Registered

2014-12-09

Start date

2014-12-31

Completion date

2019-01-31

Last updated

2019-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Keywords

Radiation, Prognosis, Palliative Care

Brief summary

Understanding patient's prognosis is of utmost importance to determine radiotherapy's indication and dose/ fractionation. The investigators plan to conduct an observational study of prognosis of inpatients evaluated for palliative radiotherapy at a large cancer hospital in Brazil.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* All inpatients evaluated for palliative radiation therapy at ICESP (Instituto do Cancer do Estado de Sao Paulo)

Exclusion criteria

* Inpatients evaluated whose intent of treatment is curative * Patients who are unwilling to participate in the study or unwilling to sign informed consent

Design outcomes

Primary

Measure	Time frame	Description
Overall Survival	9 months	Overall Survival in the studied population

Secondary

Measure	Time frame	Description
Overall Survival in Each Indication of Palliative Radiotherapy	3 months and 9 months	Overall Survival in Each Indication of Palliative Radiotherapy. The indication will be as follow: * spinal cord compression * brain metastases * tumor bleeding * tumoral mass * Oncologic Pain * Superior Vena Cava Syndrome/ Airway compression
Overall Survival by Palliative Prognostic Index (PPI)	3 months and 9 months	Patients will be divided into 3 subgroups according to the PPI. Survival differences between the different subgroups will be compared and analyzed
Overall Survival by Survival Prognostic Score (SPS)	3 months and 9 months	Patients will be divided into 3 subgroups according to the SPS. Survival differences between the different subgroups will be compared and analyzed
Overall Survival by Score Index for Stereotactic Radiosurgery for Brain Metastases (SIR)	3 months and 9 months	Patients will brain metastases will be divided into 3 subgroups according to SIR. They will be divided into SIR 0-3; 4-7;8-10. Survival differences between the different subgroups will be compared and analyzed
Positive Predictive Value of PPI	3 weeks and 6 weeks	Positive Predictive Value of PPI to predict death at 3 weeks and 6 weeks.

Countries

Brazil

Outcome results