Body Temperature Changes
Conditions
Brief summary
The objectives of this study are to demonstrate that real time physiological status monitoring and the use of optimization techniques during exercise can have a positive impact on physiological status, and to collect metabolic flexibility profiles of young fit adults during rest and exercise.
Detailed description
This experiment aims to accomplish two goals: collect additional metabolic flexibility data with young fit adults in response to exercise; and demonstrate that automated pace guidance generated from real-time thermal-work strain monitoring and an optimized pacing policy will allow less stressful completion of a timed (60 minute) treadmill exercise of 5 miles. Each participant will undergo two treatments of first UNGUIDED followed by GUIDED exercise. The two exercise sessions will be conducted as part of a \ 24 hour stay in an indirect calorimetry chamber.
Interventions
OTHERGuided Exercise Session
Participants will be provided a pace based upon their current (estimated) physiological strain index (PSI) - a measure of thermal work strain, the time, and the distance completed already.
OTHERUnguided Exercise Session
Participants will be instructed to complete 5 miles within 60 minutes and finish in as cool (lower body temperature) a state as possible.
Sponsors
United States Army Research Institute of Environmental Medicine
USDA Beltsville Human Nutrition Research Center
Study design
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 29 Years
Healthy volunteers
Yes
Inclusion criteria
* Male and Female * Ages 18 to 29 at the beginning of the study * Relatively fit can run 2 miles in under 16 minutes
Exclusion criteria
* History of Skin Sensitivity to Nickel * Hypertension * Alcoholism * Diabetes * Pregnant * Age \>29 * Cannot run 2 miles in less than 16 minutes * No regular weekly exercise * Difficulty Swallowing Food or Large Pills * Diverticulitis * Inflammatory Bowel Disease * Peptic Ulcer Disease * Crohn's Disease * Ulcerative Colitis * Previous Gastrointestinal Surgery * Possible Nuclear Magnetic Resonance Scan * Women who have given birth during the previous 12 months * Pregnant women or women who plan to become pregnant or become pregnant during the study * Lactating women * History or presence of kidney disease, liver disease, certain cancers, gastrointestinal, pancreatic, other metabolic diseases, or malabsorption syndromes * History of bariatric or certain other surgeries related to weight control * Smokers or other tobacco users (for at least 6 months prior to the start of the study) * History of eating disorders or other dietary patterns which are not consistent with the dietary intervention (e.g., vegetarians, very low fat diets, high protein diets) * Volunteers who have lost 10% of body weight within the last 12 months or who plan to initiate a weight loss program during the next 10 months * Unable or unwilling to give informed consent or communicate with study staff. * Self-report of alcohol or substance abuse within the past 12 months and/or current acute treatment or rehabilitation program for these problems (long-term participation in Alcoholics Anonymous is not an exclusion) * Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigator may interfere with study participation or the ability to follow the intervention protocol * Blood donation within the previous month
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Physiological Strain Index (PSI) | During 2-hour exercise session | The PSI is an index that combines heart rate and core body temperatures with equal weights into an index from 0 to 10+. PSI will be calculated according to Moran et al. (1998) from measures of heart rate and core body temperature. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Continuous Glucose Monitoring | 24 hours | Continuous glucose monitoring will be used to examine the effects of the exercise regime on blood glucose. |
| Self Perception Scales | During 2-hour exercise session | Self perception scales will be used that measure mood state, perceived exertion, thermal sensation, physical stresses and motivation. |
| Profile of Mood States (POMS) Questionnaire | During 2-hour exercise session | The POMS is an inventory of subjective mood states (McNair, Lorr and Droppleman, 1992). |
| Metabolic Flexibility | 24 hours | O2 utilization and CO2 production will be analyzed during each calorimeter stay and used to measure metabolic rate indirectly. |
| Perceived Exertion Scale | During 2-hour exercise session | The Borg (1970) rating of perceived exertion (RPE) will be used. |
| Feeling Scale | During 2-hour exercise session | The feeling scale will be used as an affective valence measure of exercise. |
| Motivation | During 2-hour exercise session | Question will be asked to assess motivation during each exercise session. |
| Thermal Sensation Scale | During 2-hour exercise session | Two thermal sensation scales (original and modified) will be used to assess the thermal sensation of volunteers. |
Countries
United States
Outcome results
None listed