Sputum Purulence as a Predictor of Cystic Fibrosis Exacerbations: a Prospective Cohort Trial.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02309229

Acronym

MucoSpuCo

Enrollment

Registered

2014-12-05

Start date

2012-12-31

Completion date

2014-01-31

Last updated

2014-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cystic Fibrosis

Keywords

sputum colour, cystic fibrosis, pollution

Brief summary

To use the sputum colour chart as a predictor for cystic fibrosis exaerbations

Detailed description

Patients will score their sputum purulence daily using three colour charts. They will also score for respiratory and other symptoms. Primary analysis will focus on the predicting value of sputum purulence on exacerbations. Secondary analysis will evaluate symptoms on exacerbation prediction. A third subanalysis will focus on correlation of daily pollution fluctuations and sputum purulence or symptoms.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* a diagnosis of cystic fibrosis * Pseudomonas aeruginosa colonization * at least 2 exacerbations in the previous year * at least 18 years of age

Exclusion criteria

* colour blindness

Design outcomes

Primary

Measure	Time frame
sputum colour evoluation as a predictor for exacerbation	6 months

Secondary

Measure	Time frame
symptoms as a predictor for exacerbations	6 months

Other

Measure	Time frame
pollution and symptoms/exacerbations	6 months

Countries

Belgium

Outcome results