Effect of DHA Supplementation on Cognitive Performance and Growth in Chinese Children

Effect of Dietary DHA Supplementation on Cognitive Performance and Growth in Chinese School Children: A Randomized Controlled Study

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02308930

Enrollment

106

Registered

2014-12-05

Start date

2014-07-31

Completion date

2015-10-31

Last updated

2014-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

The purpose of this study is to determine whether DHA supplement (in a daily dose of 300 mg) will improve the cognitive performance, associated metabolism and growth in normal children aged 6-12 years in primary schools.

Interventions

DIETARY_SUPPLEMENTVitamins + DHA supplement (Vitamins A,D, E and algal oil)

DIETARY_SUPPLEMENTVitamins supplement (Vitamins A,D, E and corn oil)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

6 Years to 12 Years

Healthy volunteers

Inclusion criteria

1. Children aged 6-12 years from primary schools. 2. Healthy as assessed by a physician. 3. Willing to participate in the study, consume the test product and perform all measurements including cognitive testing, blood drawing, urine samples, anthropometry and questionnaires. 4. Willing to maintain current dietary habits and intend to stay in the study area for ≥ one year. 5. Informed consent signed by parent or caregiver and oral consent given by child.

Exclusion criteria

1. Children with obvious mental and physical handicaps. 2. Children taking medication which interferes with study measurements (e.g., psychoactive medications or medications expected to affect behavior and learning). 3. Taking dietary supplements already. 4. Suffering major life events (immediate family death, parents divorce, etc.) within six months.

Design outcomes

Primary

Measure	Time frame	Description
Performance on Wisconsin card sorting test (WCST) and digit span test	6 months	At baseline, 3 and 6 months cognitive tests will be administered, and the scores of Wisconsin card sorting test (WCST) and digit span test will be recorded.

Secondary

Measure	Time frame	Description
DHA related metabolites and neurotransmitters (blood concentration of DHA related metabolites and neurotransmitters)	6 months	At baseline and 6 months, blood samples will be drawn and the concentration of DHA related metabolites and neurotransmitters will be detected using biochemical methods.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 25, 2026