Retinal Therapy Guided by 3D OCT Image Analysis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02308215

Enrollment

Registered

2014-12-04

Start date

2010-07-31

Completion date

2018-07-05

Last updated

2019-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Age-Related Macular Degeneration, Choroidal Neovascularization

Keywords

Retina, AMD, OCT

Brief summary

The main purpose is to find a better way to predict the timing of treatments given to patients with Wet Age-related macular degeneration using image analysis.

Detailed description

The study focuses on making better use of advanced three-dimensional imaging and analysis to allow physicians to know when a treatment is being effective and thus not overuse it. The study will examine how 3-D optical coherence tomography and related image analysis can be used to assess changes in the macula and retina of patients' eyes. These changes can reveal how well a person is responding to anti-VEGF treatment and thus help doctors provide proper treatment timing and care.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

45 Years to 120 Years

Healthy volunteers

Inclusion criteria

* fundoscopically confirmed AMD and patient eligible for treatment with anti-VEGF

Exclusion criteria

* Patients with a CNV due to other causes (OHS, trauma) * eyes that have been previously treated for CNV

Design outcomes

Primary

Measure	Time frame
Measure central retinal layer thickness in µms.	one year
Measure amount of fluid in the retina in µms.	one year

Countries

United States

Outcome results