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Lidocaine Spray on an Endoscope to Improve Tolerance to Endoscopy

Does Use of Lidocaine Spray on an Endoscope Immediately Before Insertion Improve Patient Tolerance to Endoscopy? A Single Center, Case-Control Study.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02307773
Enrollment
497
Registered
2014-12-04
Start date
2013-11-30
Completion date
2014-05-31
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C.Medical Procedure; Digestive System, Disorder of Upper Gastrointestinal Tract, Tolerance

Keywords

Upper Gastrointestinal Endoscopy, Pharyngeal Anesthesia, Lidocaine, Belching, Retching, Tolerance

Brief summary

The investigators tested whether a new method which additional lidocaine spray on the tip of endoscope can increase the tolerance of examinee during endoscopy than conventional pharyngeal anesthesia alone.

Detailed description

All the patients underwent upper gastrointestinal endoscopy were consecutively enrolled and assigned to case group treated with additional 2 puffs of the 10% lidocaine spray on the tip of endoscope before intubation or control group with conventional pharyngeal anesthesia without further treatment. And the investigators compared their baseline characteristics, past history, sedation or not, and frequency of retching and belching were measured during the endoscopy.

Interventions

Consecutively, all the participants were assigned to case group with additional 2 puffs of the 10% lidocaine spray on the tip of endoscope, same medication which was used for prior pharyngeal anesthesia, or to control group with conventional pharyngeal anesthesia without further treatment. Then we compared the primary outcome measures, such as, frequency of belching and retching of two groups.

Sponsors

Cheju Halla General Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
16 Years to 89 Years
Healthy volunteers
No

Inclusion criteria

* All the patients who underwent upper gastrointestinal endoscopy in Endoscopy Room, Cheju Hall General Hospital.

Exclusion criteria

* advanced older or younger age (\> 90, or \< 15 years) * comorbidities scored greater than III of American Society of Anestheiologists Physical Status Classification System (ASA) score * history of hypersensitivity reaction to lidocaine * he pregnant * therapeutic or emergency endoscopy

Design outcomes

Primary

MeasureTime frameDescription
Frequency of Belching and retchingParticipants will be followed for the duration of hospital stay, expected average of 1-2 hoursBelching was defined as release of gas from the digestive tract (mainly esophagus and stomach) through the mouth and retching was defined as reverse peristaltic movement of the stomach and esophagus without vomiting.

Secondary

MeasureTime frameDescription
Adverse eventsParticipants will be followed for the duration of hospital stay, expected average of 1-2 hoursEvents suspected as Aspiration pneumonia, methemoglobinemia

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026