Fluorescent Visualization in Early Oral Cancer

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02306967

Enrollment

Registered

2014-12-03

Start date

2011-09-30

Completion date

2017-12-31

Last updated

2018-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Squamous Cell Carcinoma or Severe Dysplasia

Keywords

oral cancer, oral dysplasia

Brief summary

Studies from Vancouver show that fluorescent visualization (FV) is a useful method of controlling surgical margins. This early finding will now be confirmed in a national randomized controlled trial.

Interventions

PROCEDUREresection of oral cancer

Oral cancer will be resected.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* biopsy proven invasive oral cancer or severe dysplasia / Cis * invasive cancer must be T1 or T2 * no prior history of oral cancer / treatment of oral cancer

Exclusion criteria

* prior history of oral cancer * unable to provide informed consent * lesion not able to be completely visualized by FV

Design outcomes

Primary

Measure	Time frame	Description
disease specific survival	5 years	disease specific 5 year survival

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026