ICSI AZOOSPERMIA VARICOCELE
Conditions
Keywords
VARICOCELE-AZOOSPERMIA-ICSI
Brief summary
This study will include cryopreserved sperm from infertile azoospermic men, with proven diagnosis of varicocele (clinical & sonographic), which will be used for ICSI in an ART program in Sohag. Patients personal and medical history and socio-demographic data will be retrieved from their saved medical files.
Detailed description
Study approval: The study will be submitted for approval by Research and Ethical committees at Faculty of Medicine, Sohag University. This study will include cryopreserved sperm from infertile azoospermic men, with proven diagnosis of varicocele (clinical & sonographic), which will be used for ICSI in an ART program in Sohag . Patients personal and medical history and socio-demographic data will be retrieved from their saved medical files. Study design: Prospective, controlled clinical study. Control group: ICSI cases using cryopreserved sperms from infertile azoospermic men due to etiologies other than varicocele. Cases with known female factor infertility will be excluded. Outcome Measures: fertilization rate, embryo quality, chemical pregnancy and clinical pregnancy.
Interventions
PROCEDUREICSI
Intracytoplasmic Sperm Injection
Sponsors
Sohag University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* cryopreserved sperm from infertile azoospermic men, with proven diagnosis of varicocele (clinical & sonographic), which will be used for ICSI in aى ART program. * ICSI cases using cryopreserved sperms from infertile azoospermic men due to etiologies other than varicocele.
Exclusion criteria
* Cases with known female factor infertility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy: documentation of gestational sac and fetal pulsation by transvaginal US 15 days after B-HCG assessment. | 6/2014 up to one year. |
Secondary
| Measure | Time frame |
|---|---|
| Fertilization Rate: percentage of fertilized oocyte. | 6/2014 up to one year. |
| Embryo Quality: morphological assessment of the developing embryo. | 6/2014 up to one year. |
| Chemical pregnancy: B-human chorionic gonadotropin (B-HCG) at day 15 after embryo transfer. | 6/2014 up to one year. |
Countries
Egypt
Contacts
Primary ContactMohamed Alhussini, M.B.B.Ch.
Backup ContactRamadan Saleh, MD
Outcome results
None listed