Cardiovascular Health Improvement Project

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02306200

Acronym

CHIP

Enrollment

15000

Registered

2014-12-03

Start date

2013-08-01

Completion date

2053-08-01

Last updated

2026-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Aneurysm, Aortic Dissection, Bicuspid Aortic Valve (BAV), Cardiovascular Diseases, Heart Failure

Keywords

Aorta, Abdominal Aortic Aneurysm (AAA), Thoracic Aortic Aneurysm (TAA), Bicuspid Aortic Valve (BAV), Aortic Dissection

Brief summary

The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.

Detailed description

The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls. The aims of the study are to collect biological specimens (blood, plasma, serum, aortic tissue) and family history; establish a biobank, establish a comprehensive database with information from consented patients, and provide researchers with high quality well annotated DNA samples with demographic and clinical information.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Any patient over the age of 18 who is able/willing to give informed consent * Patients \<18 years of age with parental consent and assent (if assent is applicable for their age) * Diagnosis of: * aortic pathology potentially due to a known or suspected inherited condition * Idiopathic aortic aneurysm * Interesting of novel vascular pathology in the aorta or main branches * Family history of aortic or vascular disease * Other cardiovascular disease * Healthy controls with no apparent cardiovascular disease

Exclusion criteria

\- Not willing or able to sign the consent

Design outcomes

Primary

Measure	Time frame	Description
Establishing a biobank of patients with Aortic Disease	40 years	Establish a biobank of blood, serum, plasma, tissue, and clinical data of patients with any form of aortic disease

Countries

United States

Contacts

CONTACTLauren Humphrey-Stark, BS

ljeany@med.umich.edu7342324779

CONTACTJen McNamara, MS

jlmcnama@med.umich.edu734-232-6180

PRINCIPAL_INVESTIGATORMarion A Hofmann Bowman, PhD, MD

University of Michigan

Outcome results