Effect of Perioperative Factors on the Analgesia Nociception Index

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02305576

Acronym

ANIFACT

Enrollment

600

Registered

2014-12-02

Start date

2014-01-31

Completion date

2018-12-31

Last updated

2018-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative Neurophysiological Monitoring

Brief summary

The Analgesia Nociception Index (ANI) is a new unitless marker derived from Heart Rate Variability spectral analysis, ranging between 0 and 100 and expressing the parasympathetic tone. The ANI is proposed as surrogate marker for the analgesia nociception balance. However, many perioperative factors such as medications, position, maneuvers may influence the ANI values and may lead to misinterpretation. Moreover the ability of the ANI to guide opioid dosing has never been tested. Therefore, the aim of our study is to collect in a database all the perioperative factors and to study their influence on the ANI.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients undergoing scheduled surgery

Exclusion criteria

* Non sinusal rhythm * Pace maker or defibrillator holders * Pregnancy or feeding * American Society of Anesthesiology physical status 4

Design outcomes

Primary

Measure	Time frame
Variation of the ANI index	Before and 2 minutes afer the factor occurrence

Countries

France

Contacts

Primary ContactGEORGES DACCACHE, M.D

daccachg@chu-caen.fr+ 33 2 31 06 47 36

Outcome results