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Physical Exercise and Pollution: Cardiorrespiratory, Cerebral and Molecular Aspects

Physical Exercise and Pollution: Cardiorrespiratory, Cerebral and Molecular Aspects.

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02304731
Enrollment
45
Registered
2014-12-02
Start date
2013-02-28
Completion date
2014-07-31
Last updated
2014-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Function 1, Social

Keywords

Physical Exercise, Atmospheric Pollution, Cognition.

Brief summary

Modern society increasingly seeks healthy life style, and regular physical activity is considered one of the main factors that improve the quality of life. The evidence shows that the aerobic physical training in controlled environments benefit various aspects of human health, including cognition in the elderly population. However, when exercise is performed in a polluted environment, the individual is subjected to grater exposure to pollutants due to increased ventilation (breathing).

Detailed description

Modern society increasingly seeks healthy life style, and regular physical activity is considered one of the main factors that improve the quality of life. The evidence shows that the aerobic physical training in controlled environments benefit various aspects of human health, including cognition in the elderly population. However, when exercise is performed in a polluted environment, the individual is subjected to grater exposure to pollutants due to increased ventilation (breathing). It is well known that inhaled pollutants can cause oxidative modification in biomolecules and oxidative stress is a cause of diverse diseases. This scenario raises important questions: the deleterious effects of pollution can abolish the beneficial effects of exercise? This issue is currently relevant given the increasing level of air pollution in large urban centers such as Sao Paulo city and at the same time, outdoor physical activity in public places is largely stimulated by public organizations, particularly for elderly. Thus this multidisciplinary project aims to investigate the deleterious effects of urban air pollution in elderly people who practice aerobic physical exercise outdoors in Sao Paulo and compare with those who practice in Laboratory. This study can provide important knowledge for public health and welfare of the population.

Interventions

OTHERPhysical Exercise

Incremental running

Sponsors

University of Sao Paulo
CollaboratorOTHER
Federal University of São Paulo
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

Health Subjects that lives in São Paulo city for at least 10 years. \-

Exclusion criteria

Neuropsychological issues. \-

Design outcomes

Primary

MeasureTime frameDescription
Cognitive Benefits12 weeksNeuropsychological Tests applied at the beginning and at the end of protocol

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026