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Predictive Factors and Autonomy Level Change

Predictive Factors of the Autonomy Level Change Related to Memory Disorders

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02302482
Acronym
MEMORA
Enrollment
10860
Registered
2014-11-27
Start date
2014-11-30
Completion date
2027-11-30
Last updated
2021-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Memory Impairment

Keywords

Alzheimer's disease or related disorders, Functional autonomy level, Cognitive function, Predictive factors

Brief summary

The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The investigators aimed at developing a database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative personal and with the University hospital computer science department. The main objective is to study the predictive factors associated with the change of functional autonomy level, measured every 6 months to 12 months by phone, in a Memory Clinic. The study population would consist in about 1000 patients with ADRD. The length of follow-up of each patient will be 3 years.

Interventions

OTHERThe Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6

Sponsors

Hospices Civils de Lyon
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients who undergo a medical visit in the Memory Clinic for the 1st time * Patients living at home or in housing * Patients with memory impairment, at all stage of the disease

Exclusion criteria

* Patients in institution * Patients under legal protection * Patients with a hearing or visual impairment, which dot not allow to carry out the examination

Design outcomes

Primary

MeasureTime frameDescription
Functional autonomy level3 yearsThe scores of Lawton Instrumental Activities of Daily Living (IADL) and of Disability Assessment of Dementia (DAD-6)

Secondary

MeasureTime frameDescription
Cognitive function level3 yearsMini Mental Test examination (MMSE)

Countries

France

Contacts

Primary ContactPierre Krolak-Salmon, Professor
pierre.krolak-salmon@chu-lyon.fr(0)4 72 43 20 50
Backup ContactVirginie Dauphinot, Doctor
virginie.dauphinot@chu-lyon.fr(0)4 72 43 20 50

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 2, 2026