Healthy
Conditions
Keywords
healthy volunteers, critical awareness, hypnosis, Analgesia Nociception Index, numerical verbal scale, Determine the validity of the index (ANI), nociception in critical awareness
Brief summary
Healthy subjects should assess pain on a numerical scale (EN), during painful skin stimuli of variable intensity delivered by a CO2 laser used at the power of 0.3 W, known for its safety. ANI (Analgesia Nociception Index) will be raised simultaneously. This sequence will be made on subjects at rest and in a state of hypnosis using the technique of remembering a pleasant memory and the ideo-sensory technique of protective glove. The average value of the ANI will be compared to the value of the EVN of pain intensity.
Interventions
DEVICECO2 laser and ANI monitor
Painful skin stimuli of variable intensity will be delivered by a CO2 laser used at the power of 0.3 W for each stimulation (6/phases) and this for each of the 3 phases (critical consciousness or hypnosis). During each stimulation, ANI values will be identified by the Physiodoloris ® monitor, through 3 standard ECG electrodes placed on the thorax of the subject.
Sponsors
University Hospital, Brest
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Knowledge of the state of hypnosis * Healthy volunteers * Capable adults * Free and informed consent
Exclusion criteria
* Heart diseases * Medication affecting the heart rate * Medication affecting the skin sensitivity
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| EVN value of pain intensity versus average value of the ANI | ANI average value : measured continuously for 60 seconds after the painful stimulation. EVN value : raised a few seconds after the painful stimulation | ANI value (0 to 100, without unit of measure) recorded continuously for 60 seconds after the painful stimulation compared to the EVN value of the pain intensity, from zero to ten (numerical verval scale), and this for each of 6 painful stimuli intensities of each three consecutive phases of the study. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| EVN value of the arduousness of pain perception versus ANI value | ANI average value : measured continuously for 60 seconds after the painful stimulation. EVN value : raised a few seconds after the painful stimulation | EVN value of the arduousness of pain perception, from zéro to ten, for a stimulation intensity, depending on the phase of the study, compared to the ANI. |
Countries
France
Outcome results
None listed