Study on Short Chain Fatty Acids Concentration in Breast Milk and Its Correlation With the Maternal Diet

Short Chain Fatty Acids in Breast Milk

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02301728

Enrollment

100

Registered

2014-11-26

Start date

2014-12-31

Completion date

2015-05-31

Last updated

2014-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Short Chain Fatty Acids Concentration in Breast Milk

Keywords

breast milk, short chain fatty acids, maternal diet

Brief summary

The purpose of this study is to determine whether the acetate, butyrate and propionate concentration in breast milk and to evaluate the possible correlation of these concentrations with maternal diet.

Interventions

OTHERsampling of breast milk, obtaining information about the maternal diet

take samples of 3 ml breast milk and 3-days diet diaries

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Yes

Inclusion criteria

* parturients women at term hospitalized in the Department of Obstetrics, Gynecology and Pathophysiology of Human Reproduction, Federico II University of Naples.

Exclusion criteria

* infections, * diabetes and other chronic diseases at the level of each organ or system, * diseases of pregnancy. * antibiotics, prebiotics, probiotics and synbiotics in the 30 days prior to the first observation.

Design outcomes

Primary

Measure	Time frame
butyrate, acetate and propionate concentration	10 days after delivery and every 30 days until the fifth month after delivery

Secondary

Measure	Time frame	Description
Relationship between short chain fatty acids in breast milk and maternal diet (amount of fibers in maternal diet and based on this it will evaluate the variations in short chain fatty acids concentration)	10 days after delivery and every 30 days until the fifth month after delivery	Relationship between short chain fatty acids in breast milk and maternal diet will be measured by assessing the amount of fibers in maternal diet and based on this it will evaluate the variations in short chain fatty acids concentration. These assessments will be carried out by using a food diary carefully compiled by mothers before each sampling of breast milk

Countries

Italy

Contacts

Primary ContactAnnalisa Passariello, MD, PhD

annalisa.passariello@unina.it+ 39 081 746 2680

Backup Contactroberto berni canani, MD, PhD

berni@unina.it+ 39 081 746 2680

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026