Postoperative Hypoxia
Conditions
Brief summary
A prospective cohort pilot study of non-cardiac patients to determine the feasibility of recruiting 150 patients to undergo postoperative continuous hemodynamic monitoring for up to 3 days.
Detailed description
Patient will start wearing the Philips' hemodynamic and ECG monitor in the Post Anaesthesia Care Unit (PACU). This device will continuously measure heart rate, pulse oxymetry, and ST-segments. The device will measure blood pressure every hour from 7 am to 10 pm and every 2 hours from 10 pm to 7 am. Patients will have postoperative Troponin I monitoring and telephone follow-up at 30 days postop.
Interventions
OTHERECG, blood pressure and oximetry
Sponsors
Hamilton Health Sciences Corporation
McMaster University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
45 Years to No maximum
Healthy volunteers
No
Inclusion criteria
We will enroll patients aged 45 years or older undergoing noncardiac surgery who fulfilled 2 or more of the following risk factors: * History of coronary artery disease * History of stroke or transient ischemic attack (TIA) * History of hypertension * History of diabetes * History of peripheral vascular disease * History of congestive heart failure * Preoperative creatinine \> 175 umol/L * A planned admission for ≥48 hours * Patients receiving a general or regional anesthetic
Exclusion criteria
* Patients unable to provide informed consent. * Patients who undergo procedure performed under infiltrative or topical anesthesia. * Patients previously enrolled in the HI-VISION Study. * Patients who refuse 30-day follow-up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hypotension and Hypoxemia (baseline patterns and frequencies) | 10 months | To identify baseline patterns and frequencies of hypotension and hypoxemia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Myocardial Ischemia (association between myocardial ischemia detected by the algorithm implemented by MX40 with Troponin I) | 10 months | To determine the association between myocardial ischemia detected by the algorithm implemented by MX40 with Troponin I. |
| Myocardial Ischemia (delay in detecting myocardial ischemia based on MX40 monitoring versus Troponin I monitoring) | 10 months | To determine the delay in detecting myocardial ischemia based on MX40 monitoring versus Troponin I monitoring. |
| Myocardial Ischemia (number of patients with missed clinically important hypotension, bradycardia, and hypoxia based on routine monitoring in clinical practice versus remote, automated, non-invasive hemodynamic monitoring) | 10 months | To determine the number of patients with missed clinically important hypotension, bradycardia, and hypoxia based on routine monitoring in clinical practice versus remote, automated, non-invasive hemodynamic monitoring. |
| Myocardial Ischemia (delay in detecting clinically important hypotension, bradycardia, and hypoxia based on routine monitoring in clinical practice versus remote, automated, non-invasive hemodynamic monitoring.) | 10 months | To determine the delay in detecting clinically important hypotension, bradycardia, and hypoxia based on routine monitoring in clinical practice versus remote, automated, non-invasive hemodynamic monitoring. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Pain (association between postoperative pain intensity and myocardial ischemia, nonfatal myocardial infarction, and cardiac mortality) | 10 months | To determine the association between postoperative pain intensity and myocardial ischemia, nonfatal myocardial infarction, and cardiac mortality. |
Countries
Canada
Outcome results
None listed