Memory Disorders, Alzheimer Disease
Conditions
Brief summary
This study aims to prospectively examine the memory problem perceptions of patients with memory complaints \[MCs\] and their accompaniers during the diagnostic process.
Detailed description
Through the french adaptation of the illness perception questionnaire memory, this study aims to prospectively examine the memory problem perceptions of patients with memory complaints \[MCs\] and their accompaniers during the diagnostic process. The investigators plan to recruit 125 patients with MCs who come for the first time at the Research and Resources Memory Center in Nancy, France. Participants have to express MCs and must be free of dementia diagnosis at the first visit. Participants also need to be accompanied by an accompanier and both have to be fluent in French. This study has been approved by our local Ethics Committee (Committee for the Protection of Persons) and the French Health Security Agency. After giving their informed consent, patients and accompaniers are followed up throughout the diagnostic process with three visits : at their first visit, at one month after the first visit, and at six months after the diagnosis disclosure.
Interventions
BEHAVIORALPsychological questionnaires
Psychological questionnaires about memory problems perceptions, anxiety, depression, quality of life and coping
Sponsors
France Alzheimer
Laboratoire APEMAC :Maladies chroniques, santé perçue, processus d adaptation, France
Central Hospital, Nancy, France
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
For patients with memory complaints: * Age over 18 years * Have a memory complaints with a QPC score greater than or equal to 3 * Be accompanied by a next of kin * Folstein MMSE greater than or equal to 15/30 * Have given their written consent after receiving clear and intelligible oral and written information * Social security coverage For Accompaniers : * Age over 18 years * Consent to participate at the study with the patient * Have given their written consent after receiving clear and intelligible oral and written information * Social security coverage * Be in contact with the patient at least 8 hours per week. It could be physical contact or telephone contact.
Exclusion criteria
For patients with memory complaints: * Sensory deficit interfering with the completion of the questionnaires * Level of French insufficient to complete the questionnaires * Legally protected person * Diagnosis of neurocognitive disorders already established * Treatment for Alzheimer Disease * Refusal or inability to obtain written informed consent form from the patient * Included in another experimental study at inclusion visit For Accompaniers: * Sensory deficit interfering with the completion of the questionnaires * Level of French insufficient to complete the questionnaires * Refusal or inability to obtain written informed consent form from the accompanier
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Memory problems perceptions of patients and next of kin during diagnosis process | Baseline and 6 months after diagnosis disclosure | How patients and accompaniers perceive memory problems at the first visit in a Memory Center to 6 months after the diagnosis disclosure, with the Illness Perception Questionnaire Memory |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Psychometric properties of the french adaptation of the Ilness Perceptions Questionnaire - Memory (IPQ-M, Hurt et al. 2010) | Baseline, 1 month later and 6 months after diagnosis disclosure | Psychometric properties of IPQ-M by a traditional approach and by comparison to another french memory complaint questionnaire |
| Impact of the memory problems perceptions on mood and well-being | Baseline and 6 months after diagnosis disclosure | Correlation between memory problems perceptions at the IPQ-M, levels of anxiety (STAI-Y), depression (MADRS), quality of life (WHOQOL-BREF) and coping strategies. |
| Differences of memory problems perceptions and coping according to level of cognitive disorder at the Mini-Mental State Examination (MMSE) | Baseline and 6 months after diagnosis disclosure | — |
Countries
France
Contacts
Primary Contactchristine perret-guillaume, PhD, MD
Backup Contactanaick besozzi, M's D
Outcome results
None listed