Eating Behavior
Conditions
Keywords
low calorie sweetener satiety, intake, hunger
Brief summary
Although there is evidence that low calorie sweeteners (LCS) do not stimulate hunger or appetite, divergent opinions appear regularly both in the scientific literature and in the popular press. The goal of this study is to examine the effects of LCS containing beverages on appetite and intake in healthy individuals.
Detailed description
The study will be a monocentric randomized controlled open trial including two parallel groups to examine effects of LCS beverages as compared to water on daily intakes of energy and macronutrients. The effects of LCS beverages on hunger, satiety, desire to eat and on the selection of sweet or savory foods eating occasions will be assessed.
Interventions
OTHERBeverage containing low calorie sweeteners
Beverage containing low calorie sweeteners
OTHERStill water
Still water (no flavour)
Sponsors
CreaBIO
The Coca-Cola Company
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Body Mass Index: Lower limit 18 kg/m²; Upper limit 28 kg/m²; weight stable within ± 3 kg in the last 6 months * Habitual energy intake within the 95% confident interval of the reference energy intake for the French population (as provided by the INCA 2 survey * Must not be a regular drinker of LCS beverages (less than once a week no more than every 15 days) and be willing to use LCS according to protocol * For female participants: not pregnant, not breast feeding, planning to become pregnant during the study or on contraception since at least 3 months (regular 28-day cycle) * Subject registered with the French Social Security.
Exclusion criteria
* Currently diagnosed somatic pathology * On medication affecting metabolism, weight, energy intake, or energy expenditure in the last 6 months * Major psychiatric disorder, particularly eating disorders as defined by the Diagnostic and Statistical Manual od Mental Disorders-IV * Rejection of sweet foods or drinks as revealed by the diet history * Smoking subject planning to stop smoking in the next 3 months * Subjects suffering from food allergies or intolerance * Subject not capable of understanding the constraints of the study and who not agree to abide
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Subjective sensations: hunger, satiety and desire to eat | 9 weeks | Visual Analog Scales |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Energy and macronutrient intakes | 9 weeks | Diet history questionnaire |
| Anthropometric parameters | 9 weeks | body weight, height, waist and hip circumferences |
Countries
France
Outcome results
None listed