Cardiovascular Diseases
Conditions
Keywords
Risk
Brief summary
Contrary to popular belief, previous studies have demonstrated beneficial effects of whole egg consumption in modifying biomarkers indicative of a greater risk of coronary heart disease (CHD), chronic inflammation, and insulin resistance. The following study is designed to conduct a comprehensive evaluation of consuming an egg-based breakfast compared to an oatmeal-based breakfast on lipid biomarkers, oxidative stress, inflammation, insulin sensitivity, and satiety in young, healthy men and women. The investigators hypothesize that the consumption of 2 eggs per day will not negatively impact plasma lipids in a young, healthy population.
Interventions
11-week crossover study in which participants consumed 2 eggs or 1 packet of oatmeal per day daily for 4 weeks, separated by a 3-week washout period.
11-week crossover study in which participants consumed 2 eggs or 1 packet of oatmeal per day daily for 4 weeks, separated by a 3-week washout period.
Sponsors
Study design
Eligibility
Inclusion criteria
* BMI 18.5-30, willing to consume eggs and oatmeal daily, proficient in English, and with a healthy lipid profile.
Exclusion criteria
* Currently have liver disease, renal disease, diabetes, cancer, history of stroke or heart disease * Currently taking glucose lowering drugs or supplements * Plasma triglycerides \>500 mg/dL, glucose \>126, total cholesterol \>240 * Pregnant, lactating, or have endocrine or metabolic disorders * BMI ≥ 30 * Blood pressure \> 140/90 (average of 3 readings) * Allergies to eggs * Celiac disease or gluten sensitivity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spectrophotometry, NMR and ELISA will assess plasma lipids. | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Visual analog scales (VAS) and ELISA assays will assess satiety. | 1 year |
Countries
United States