Abdominal Hysterectomy (& Wertheim), Intraoperative Complications
Conditions
Brief summary
The purpose of this study is to determine the effects of Transversus Abdominis Plane Block on hemodynamic variables, anaesthetic and analgesic requirement, and quality of recovery in patients undergoing total abdominal hysterectomy
Detailed description
Pain is one of the main causes of the poor perioperative outcomes and pain management is the important part of perioperative period. Neuraxial blocks could provide adequate analgesia during and after abdominal surgery. However,neuraxial blocks have a lot of contraindicated situations and neuraxial anesthesia can easily induce hemodynamic abnormalities. Therefore, in most cases, the choice of anaesthetic management may be the general anesthesia. In addition to reduce the blood pressure and heart rate changes due to surgical stimulations, the large amount of opioids and anaesthetics may be required. Opioid related side effects can affect perioperative complications and postoperative quality of recovery. Transversus abdominis plane block is a new choice to reduce postoperative pain in abdominal surgery. Although its postoperative analgesic efficacy is well known, its effects on hemodynamic variables, anaesthetic and analgesic requirement is not clear. The main objective of this study is to estimate the effect of Transversus abdominis plane block on hemodynamic variables, anaesthetic and analgesic requirement and quality of recovery in patients undergoing total abdominal hysterectomy.
Interventions
PROCEDURETAP block
Using real time ultrasound imaging, bilateral, 20 ml 0,25% bupivacaine inject into the area between the internal oblique and transverse abdominis muscle
PROCEDUREControl
A sham band-aid will be applied to the abdomen of subjects
Sponsors
Tokat Gaziosmanpasa University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Adult (18-65years old) * American Society of Anesthesiologists (ASA) physical status I-II * Patients scheduled for elective total abdominal hysterectomy under general anesthesia
Exclusion criteria
* ASA physical status ≥ 3 * Allergy to local anesthetics * Drug abuse or addiction * Bleeding tendency
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| intraoperative opioid consumption | during anaesthesia | The overall intravenous remifentanyl consumption (microgram/ kilogram) during the surgery. The decision to administer remifentanyl is guided by the changes of blood pressure and/ or heart rate greater than 20% from baseline level. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of recovery | postoperative 24 hours | quality of recovery 40 form will use to assessment the recovery |
| Postoperative nausea and vomiting | postoperative 0.,2.,12.,24 hours | nausea score(0-3) and number of vomiting will be recorded |
| postoperative pain | postoperative 0,2,12,24 hours | visual analog scale will be used |
| intraoperative hemodynamic variables | during anaesthesia | arterial blood pressure, heart rate changes will be recorded |
| intraoperative anaesthetic consumption | during anaesthesia | anaesthetic consumption will be calculated |
Countries
Turkey (Türkiye)
Outcome results
None listed