Healthy
Conditions
Keywords
volunteers
Brief summary
To assess the bioefficacy of omega-3 fatty acids (provided by intake of fish oil supplements) depending on genotype of relevant factors in lipid metabolism
Detailed description
To assess the bioefficacy of omega-3 fatty acids (provided by intake of fish oil supplements) depending on genotype of relevant factors in lipid metabolism.
Interventions
DIETARY_SUPPLEMENTTriple Strength Fish Oil
Triple Strength Fish Oil
Sponsors
Société des Produits Nestlé (SPN)
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy adult between 18 and 40 years of age * BMI between 18.5 and 30 kg/m2 * Sedentary to moderate physical activity habits
Exclusion criteria
* Concomitant treatment: Consumption of dietary supplements or any medication that can affect the study outcomes * Actively smoking * Suspected abuse of alcohol or illicit drugs * Significant illness within the two weeks prior to study start or any active systemic infection or medical condition that may require treatment during the study * Known or suspected medical condition related to coagulation * Subject who cannot be expected to comply with the study procedures * Currently participating or having participated in another clinical trial during the last 4 weeks prior to beginning of this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in triglyceride levels in plasma | Baseline and 6 weeks intervention |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assess bioefficacy of EPA and DHA supplementation | Baseline and 6 weeks intervention | The bioefficacy will be evaluated by characterizing and measuring the effects on lipid metabolism, glucose metabolism and insulin resistance, and inflammatory response |
Outcome results
None listed