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Will Lactobacillus Increase Cure Rate After Treatment of Bacterial Vaginosis and Chronic Vulvovaginal Candida

Vaginal Colonization After Treatment With Lactobacillus in Women With BV or Candida Will That Increase the Cure Rate After Treatment With Clindamycin for BV and Flucnazole for Candida

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02295579
Enrollment
50
Registered
2014-11-20
Start date
2014-06-30
Completion date
2015-11-30
Last updated
2019-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial Vaginosis

Brief summary

From the earlier studies the investigators have treated women with bacterial vaginosis and cronic vulvovaginal candida. The investigators have then treated them with laktobacilli 10 days for 2 month. The investigators will continue to follow them and investigate if treatment with lactobacilli every week for 6 month will increase cure rate.

Detailed description

Clinical diagnosis of bacterial vaginosis using air dried smears combined with Hay/Ison classification. Test of cure every month or every menstrual cycle using self taken smears. The cure will be if the woman are in group 1 according to Hay/Ison classification. This will also allow us to use molecular diagnosis of BV to test cure and compare this with hay/Ison. Test of cure for candida patiens are no visibel candida on wet smear and free of symtoms of candida.

Interventions

OTHERlactobacillus (EcoVag)

Probiotic human lactobacillus (L. gasseri and L rahmnosus)

Sponsors

Skaraborg Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 55 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosis of bacterial vaginosis according to Hay/Ison or with candida diagnosed with wet smear.

Exclusion criteria

* Women with chlamydia infection, Pregnancy, Herpes

Design outcomes

Primary

MeasureTime frame
cure rate6 month

Secondary

MeasureTime frame
colonization of lactobacilli6 month

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 17, 2026