Endometriosis
Conditions
Keywords
deep endometriosis;, colorectal endometriosis, surgery, medical treatment, fertility
Brief summary
All women managed for endometriosis are included and followed up through the CIRENDO database. Information is obtained from surgical and histological records and from self-questionnaires completed before surgery. Standardized gastrointestinal questionnaires (KESS, GIQLI, WEXNER, FIQL and Bristol) are routinely used to assess bowel function. Data recording, patient contact and follow-up are carried out by a clinical research technician. Postoperative follow-up is based on data from the afore-mentioned questionnaires completed at 1, 3, 5 and 7 years.
Detailed description
All women managed for endometriosis are included and followed up through the CIRENDO database (the North-West Inter Regional Female Cohort for Patients with Endometriosis), a prospective cohort financed by the G4 Group (The University Hospitals of Rouen, Lille, Amiens and Caen), and coordinated by the principal investigator (H.R.). Information is obtained from surgical and histological records and from self-questionnaires completed before surgery. Standardized gastrointestinal questionnaires (KESS, GIQLI, WEXNER, FIQL and Bristol) are routinely used to assess bowel function. Data recording, patient contact and follow-up are carried out by a clinical research technician. Women are included in the CIRENDO database only when endometriosis is confirmed by both surgical exploration and biopsy. Postoperative follow-up is based on data from the afore-mentioned questionnaires completed at 1, 3, 5 and 7 years. Prospective data recording and analysis were approved by the French authorities CNIL (Commission Nationale de l'Informatique et des Libertés) and CCTIRS (Comité Consultatif pour le Traitement de l'Information en matière de Recherche dans le domaine de la Santé).
Interventions
Shaving, disc excision and colorectal resection; ureterolysis or ureter resection; bladder resection; ablation of endometriomas using plasma energy; excision and ablation of deep and superficial lesions
Sponsors
Study design
Eligibility
Inclusion criteria
* Endometriosis revealed on histological specimens
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recurrences | 7 years | rate of recurrences at 1,3,5 and 7 years postoperatively |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Risk factors for endometriosis | 1 year | Association of various antecedents with specific localizations of features of the endometriosis |
| Digestive functional outcomes | 7 years | Bowel function in patients managed for bowel endometriosis by various procedures |
| Fertility | 7 years | Rate of pregnancy at 1, 3, 5, and 7 years postoperatively |
Countries
France